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ITT4927

ITT4927
ITT4927
  • Gene/Protein: PLAGL1
  • Product Description: Immunotag™ ZAC1 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

    Available Options

ITT4927

Immunotag™ ZAC1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein ZAC1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
Specificity ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PLAGL1
Accession No. Q9UM63
Alternate Names PLAGL1; LOT1; ZAC; Zinc finger protein PLAGL1; Lost on transformation 1; LOT-1; Pleiomorphic adenoma-like protein 1; Tumor supressor ZAC
Description PLAG1 like zinc finger 1(PLAGL1) Homo sapiens This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],
Protein Expression Colon,Fetal kidney,Lung,Mammary gland,Pituitary,Placenta,
Subcellular Localization nucleus,nucleoplasm,Golgi apparatus,intracellular membrane-bounded organelle,
Protein Function function:Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 7 C2H2-type zinc fingers.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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