menu
Your Cart

ITT5081

ITT5081-2
ITT5081
ITT5081-4
ITT5081-3
ITT5081-2
ITT5081
ITT5081-4
ITT5081-3
ITT5081
  • Catalog: ITT5081
  • Gene/Protein: UBE2A/UBE2B
  • Product Description: Immunotag™ UBE2A/B Polyclonal Antibody
385.0000
Price in reward points: 385

Available Options

Immunotag™ UBE2A/B Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein UBE2A/B
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human UBE2A/B
Specificity UBE2A/B Polyclonal Antibody detects endogenous levels of UBE2A/B protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name UBE2A/UBE2B
Accession No. P49459/P63146 P63149
Alternate Names UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B;RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B
Description ubiquitin conjugating enzyme E2 A(UBE2A) Homo sapiens The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Cell Pathway/ Category Ubiquitin mediated proteolysis,
Protein Expression Lung,Skin,Subthalamic nucleus,Thyroid,
Subcellular Localization chromatin,nuclear chromatin,XY body,cytoplasm,cytosol,HULC complex,
Protein Function catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Catalyzes the covalent attachment of ubiquitin to other proteins. Required for postreplication repair of UV-damaged DNA.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,subunit:Interacts with RAD18.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

Write a review

Note: HTML is not translated!
Bad Good
Captcha

CONNECT WITH US