ITT5084
ITT5084
- Catalog: ITT5084
- Gene/Protein: SND1
- Product Description: Immunotag™ TudorSN Polyclonal Antibody
385.0000
Price in reward points: 385
Your shopping cart is empty!
Antibody Specification | |
Datasheet | |
Target Protein | TudorSN |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from the Internal region of human TudorSN |
Specificity | TudorSN Polyclonal Antibody detects endogenous levels of TudorSN protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SND1 |
Accession No. | Q7KZF4 Q78PY7 Q66X93 |
Alternate Names | SND1; TDRD11; Staphylococcal nuclease domain-containing protein 1; 100 kDa coactivator; EBNA2 coactivator p100; Tudor domain-containing protein 11; p100 co-activator |
Description | staphylococcal nuclease and tudor domain containing 1(SND1) Homo sapiens This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016], |
Protein Expression | Brain,Colon carcinoma,Epithelium,Lymph, |
Subcellular Localization | nucleus,cytoplasm,mitochondrion,cell-cell adherens junction,membrane,RISC complex,melanosome,extracellular exosome,dense body, |
Protein Function | function:Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).,PTM:Phosphorylated by PIM1 in vitro.,sequence caution:The frameshift leads to wrong initation.,similarity:Contains 1 Tudor domain.,similarity:Contains 4 TNase-like domains.,subcellular location:In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds to acidic transactivation domain of EBNA2. Interacts with EAV NSP1. Interacts with GTF2E1 and GTF2E2. Forms a ternary complex with STAT6 and POLR2A. Interacts with STAT5.,tissue specificity:Ubiquitously expressed., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |