ITT5211
ITT5211
- Catalog: ITT5211
- Gene/Protein: P2RX3
- Product Description: Immunotag™ P2X3 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | P2X3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from P2X3, at AA range: 71-120 |
Specificity | P2X3 Polyclonal Antibody detects endogenous levels of P2X3 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | P2RX3 |
Accession No. | P56373 Q3UR32 P49654 |
Alternate Names | P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor |
Description | purinergic receptor P2X 3(P2RX3) Homo sapiens The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Calcium,Neuroactive ligand-receptor interaction, |
Protein Expression | Heart, |
Subcellular Localization | integral component of nuclear inner membrane,rough endoplasmic reticulum,Golgi apparatus,plasma membrane,integral component of plasma membrane,neuronal cell body,terminal bouton,dendritic spine,receptor complex,membrane raft, |
Protein Function | function:Receptor for ATP that acts as a ligand gated ion channel.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |