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ITT5211

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ITT5211
  • Catalog: ITT5211
  • Gene/Protein: P2RX3
  • Product Description: Immunotag™ P2X3 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ P2X3 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein P2X3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from P2X3, at AA range: 71-120
Specificity P2X3 Polyclonal Antibody detects endogenous levels of P2X3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name P2RX3
Accession No. P56373 Q3UR32 P49654
Alternate Names P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor
Description purinergic receptor P2X 3(P2RX3) Homo sapiens The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Calcium,Neuroactive ligand-receptor interaction,
Protein Expression Heart,
Subcellular Localization integral component of nuclear inner membrane,rough endoplasmic reticulum,Golgi apparatus,plasma membrane,integral component of plasma membrane,neuronal cell body,terminal bouton,dendritic spine,receptor complex,membrane raft,
Protein Function function:Receptor for ATP that acts as a ligand gated ion channel.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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