ITT5244
ITT5244
- Catalog: ITT5244
- Gene/Protein: CD28
- Product Description: Immunotag™ CD28 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD28 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from T-cell-specific surface glycoprotein CD28 at AA range: 11-60 |
| Specificity | CD28 Polyclonal Antibody detects endogenous levels of CD28 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CD28 |
| Accession No. | P10747 P31041 |
| Alternate Names | CD28; T-cell-specific surface glycoprotein CD28; TP44; CD28 |
| Description | CD28 molecule(CD28) Homo sapiens The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011], |
| Cell Pathway/ Category | Cell adhesion molecules (CAMs),T_Cell_Receptor,Intestinal immune network for IgA production,Type I diabetes mellitus,Autoimmune thyroid disease,Systemic lupus erythematosus,Allograft rejection,Graft-versus-host disease,Viral myocarditis, |
| Protein Expression | Peripheral blood T-cell,T-cell, |
| Subcellular Localization | immunological synapse,cytosol,plasma membrane,integral component of plasma membrane,external side of plasma membrane,cell surface,protein complex involved in cell adhesion, |
| Protein Function | function:Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.,online information:CD28 entry,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70.,tissue specificity:Expressed in T-cells and plasma cells, but not in less mature B-cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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