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ITT5427

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ITT5427
  • Catalog: ITT5427
  • Gene/Protein: MYH1/MYH2/MYH3/PTPRJ/MYH6/MYH7/MYH8
  • Product Description: Immunotag™ MYH-pan Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ MYH-pan Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein MYH-pan
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from human MYH-pan around the non-acetylation site of K1394
Specificity MYH-pan Polyclonal Antibody detects endogenous levels of MYH-pan protein only when acetylation at K1394.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name MYH1/MYH2/MYH3/PTPRJ/MYH6/MYH7/MYH8
Accession No. P12882/Q9UKX2/P11055/Q9Y623/P13533/P12883/P13535 P12847/Q29RW1
Alternate Names MYH1; Myosin-1; Myosin heavy chain 1; Myosin heavy chain 2x; MyHC-2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain, skeletal muscle, adult 1; MYH2; MYHSA2; Myosin-2; Myosin heavy chain 2Myosin heavy chain 2; Myosin heavy chain 2a; MyHC-2a; Myosin heavy chain IIa; MyHC-IIa; Myosin heavy chain, skeletal muscle, adult 2; MYH3; Myosin-3; Muscle embryonic myosin heavy chain; Myosin heavy chain 3
Description myosin heavy chain 1(MYH1) Homo sapiens Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Tight junction,Viral myocarditis,
Protein Expression Skeletal muscle,
Subcellular Localization muscle myosin complex,intercalated disc,myosin complex,A band,myosin filament,cytoplasmic ribonucleoprotein granule,
Protein Function domain:The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.,function:Muscle contraction.,miscellaneous:Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subcellular location:Thick filaments of the myofibrils.,subunit:Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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