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ITT5510

ITT5510-2
ITT5510-3
ITT5510
ITT5510-2
ITT5510-3
ITT5510
ITT5510
  • Gene/Protein: LILRB5
  • Product Description: Immunotag™ CD85c Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ CD85c Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD8500c
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB5. AA range:21-70
Specificity CD85c Polyclonal Antibody detects endogenous levels of CD85c protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name LILRB5
Accession No. O75023
Alternate Names LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c
Description leukocyte immunoglobulin like receptor B5(LILRB5) Homo sapiens This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Protein Expression Pancreas,Peripheral blood leukocyte,Plasma,Small intestine,
Subcellular Localization integral component of membrane,
Protein Function domain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:May act as receptor for class I MHC antigens.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected in a natural killer (NK) cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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