ITT5639
ITT5639
- Catalog: ITT5639
- Gene/Protein: ENPEP
- Product Description: Immunotag™ CD249 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CD249 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Glutamyl aminopeptidase at AA range: 671-720 |
Specificity | CD249 Polyclonal Antibody detects endogenous levels of CD249 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ENPEP |
Accession No. | Q07075 P16406 P50123 |
Alternate Names | ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249 |
Description | catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues., |
Cell Pathway/ Category | Renin-angiotensin system, |
Protein Expression | Kidney,Kidney cortex,Liver,Placenta,Plasma, |
Subcellular Localization | lysosomal membrane,plasma membrane,integral component of plasma membrane,brush border,external side of plasma membrane,integral component of membrane,apical plasma membrane,cytoplasmic vesicle,apical part of cell,extracellular exosome, |
Protein Function | catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |