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ITT5639

ITT5639-3
ITT5639
ITT5639-2
ITT5639-3
ITT5639
ITT5639-2
ITT5639
  • Catalog: ITT5639
  • Gene/Protein: ENPEP
  • Product Description: Immunotag™ CD249 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ CD249 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD249
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from Glutamyl aminopeptidase at AA range: 671-720
Specificity CD249 Polyclonal Antibody detects endogenous levels of CD249 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name ENPEP
Accession No. Q07075 P16406 P50123
Alternate Names ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249
Description catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.,
Cell Pathway/ Category Renin-angiotensin system,
Protein Expression Kidney,Kidney cortex,Liver,Placenta,Plasma,
Subcellular Localization lysosomal membrane,plasma membrane,integral component of plasma membrane,brush border,external side of plasma membrane,integral component of membrane,apical plasma membrane,cytoplasmic vesicle,apical part of cell,extracellular exosome,
Protein Function catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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