ITT5699
ITT5699
- Catalog: ITT5699
- Gene/Protein: HGF
- Product Description: Immunotag™ HGF Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HGF |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human HGF. AA range:500-600 |
| Specificity | HGF Polyclonal Antibody detects endogenous levels of HGF protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | HGF |
| Accession No. | P14210 Q08048 |
| Alternate Names | HGF; HPTA; Hepatocyte growth factor; Hepatopoietin-A; Scatter factor; SF |
| Description | hepatocyte growth factor(HGF) Homo sapiens This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Focal adhesion,Pathways in cancer,Renal cell carcinoma,Melanoma, |
| Protein Expression | Brain,Embryonic fibroblast,Leukocyte,Liver,Lung fibroblast,Placenta, |
| Subcellular Localization | extracellular region,extracellular space,membrane,platelet alpha granule lumen, |
| Protein Function | function:HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.,online information:Hepatocyte growth factor entry,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 PAN domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 4 kringle domains.,subunit:Dimer of an alpha chain and a beta chain linked by a disulfide bond., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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