ITT5710
ITT5710
- Catalog: ITT5710
- Gene/Protein: C5AR1
- Product Description: Immunotag™ CD88 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CD88 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human C5AR1. AA range:1-50 |
Specificity | CD88 Polyclonal Antibody detects endogenous levels of CD88 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | C5AR1 |
Accession No. | P21730 P30993 |
Alternate Names | C5AR1; C5AR; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88 |
Description | function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family., |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction,Complement and coagulation cascades, |
Protein Expression | Brain, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,cell surface,cytoplasmic, membrane-bounded vesicle,basolateral plasma membrane,cytoplasmic vesicle,apical part of cell, |
Protein Function | function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |