ITT5719
ITT5719
- Catalog: ITT5719
- Gene/Protein: CLEC11A
- Product Description: Immunotag™ SCGF Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | SCGF |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from C-type lectin domain family 11 member A at AA range: 1-50 |
Specificity | SCGF Polyclonal Antibody detects endogenous levels of SCGF protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CLEC11A |
Accession No. | Q9Y240 O88200 O88201 |
Alternate Names | CLEC11A; CLECSF3; LSLCL; SCGF; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; Lymphocyte secreted C-type lectin; Stem cell growth factor; p47 |
Description | C-type lectin domain family 11 member A(CLEC11A) Homo sapiens This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008], |
Protein Expression | Bone marrow,Skin, |
Subcellular Localization | extracellular region,extracellular space,cytoplasm, |
Protein Function | developmental stage:In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.,function:Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.,online information:Stem cell growth factor,PTM:O-glycosylated. Probably sulfated on the O-glycans.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |