ITT5740
ITT5740
- Catalog: ITT5740
- Gene/Protein: SSTR2
- Product Description: Immunotag™ SSTR2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SSTR2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from SSTR2, at AA range: Internal |
| Specificity | SSTR2 Polyclonal Antibody detects endogenous levels of somatostatin receptor 2 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SSTR2 |
| Accession No. | P30874 P30875 P30680 |
| Alternate Names | Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1) |
| Description | somatostatin receptor 2(SSTR2) Homo sapiens Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Eye, |
| Subcellular Localization | cytoplasm,plasma membrane,integral component of plasma membrane,neuron projection, |
| Protein Function | function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:The C-terminus interacts with SHANK1 PDZ domain.,tissue specificity:Cerebrum and kidney. In lesser amounts in jejunum, colon and liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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