ITT5895
ITT5895
- Catalog: ITT5895
- Gene/Protein: IL19 ZMDA1
- Product Description: Immunotag™ IL-19 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | IL-19 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | Synthetic peptide from human protein at AA range: 51-100 |
Specificity | The antibody detects endogenous IL-19 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | IL19 ZMDA1 |
Accession No. | Q9UHD0 Q8CJ70 |
Alternate Names | Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1) |
Description | interleukin 19(IL19) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Jak_STAT, |
Subcellular Localization | extracellular region,extracellular space, |
Protein Function | function:May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.,similarity:Belongs to the IL-10 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |