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ITT5918

ITT5918-3
ITT5918
ITT5918-2
ITT5918-3
ITT5918
ITT5918-2
ITT5918
  • Catalog: ITT5918
  • Gene/Protein: CXCL1 GRO GRO1 GROA MGSA SCYB1
  • Product Description: Immunotag™ GROα Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ GROα Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GROα
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution IHC-p 1:50-200, ELISA 1:10000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthetic peptide from human protein at AA range: 70-107
Specificity The antibody detects endogenous GROα
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CXCL1 GRO GRO1 GROA MGSA SCYB1
Accession No. P09341 P12850
Alternate Names Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)]
Description C-X-C motif chemokine ligand 1(CXCL1) Homo sapiens This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014],
Cell Pathway/ Category Cytokine-cytokine receptor interaction,Chemokine,NOD-like receptor,Epithelial cell signaling in Helicobacter pylori infection,
Protein Expression Blood,Ovary,Peripheral blood monocyte,Placenta,Skin,
Subcellular Localization extracellular region,extracellular space,intracellular,
Protein Function function:Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.,online information:CXCL1 entry,PTM:N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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