ITT5954
ITT5954
- Catalog: ITT5954
- Gene/Protein: IL37 FIL1Z IL1F7 IL1H4 IL1RP1
- Product Description: Immunotag™ IL-1F7 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | IL-1F7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 101-150 |
| Specificity | The antibody detects endogenous IL-1F7 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | IL37 FIL1Z IL1F7 IL1H4 IL1RP1 |
| Accession No. | Q9NZH6 |
| Alternate Names | Interleukin-37 (FIL1 zeta) (IL-1X) (Interleukin-1 family member 7) (IL-1F7) (Interleukin-1 homolog 4) (IL-1H) (IL-1H4) (Interleukin-1 zeta) (IL-1 zeta) (Interleukin-1-related protein) (IL-1RP1) (Interleukin-23) (IL-37) |
| Description | interleukin 37(IL37) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008], |
| Protein Expression | Colon carcinoma,Fetal B-cell,Fetal colon,Fetal lung,Fetal testis,Placenta, |
| Subcellular Localization | extracellular region,extracellular space,nucleus,nucleolus,cytoplasm,cytosol, |
| Protein Function | function:Binds to interleukin-18 receptor (IL-18R) receptor but not to IL-1 receptor. Could be a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis.,induction:By phorbol ester (PMA) in different cell lines.,miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,tissue specificity:Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node. Isoform D and isoform E were found only in testis and bone marrow. Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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