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ITT6007

ITT6007
ITT6007-2
ITT6007
ITT6007-2
  • Gene/Protein: CSF2 GMCSF
  • Product Description: Immunotag™ GM-CSF Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

    Available Options

ITT6007

Immunotag™ GM-CSF Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GM-CSF
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution IHC-p 1:50-200, ELISA 1:10000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthetic peptide from human protein at AA range: 100-144
Specificity The antibody detects endogenous GM-CSF
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CSF2 GMCSF
Accession No. P04141 P01587
Alternate Names Granulocyte-macrophage colony-stimulating factor (GM-CSF) (Colony-stimulating factor) (CSF) (Molgramostin) (Sargramostim)
Description colony stimulating factor 2(CSF2) Homo sapiens The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Cytokine-cytokine receptor interaction,Jak_STAT,Hematopoietic cell lineage,Natural killer cell mediated cytotoxicity,T_Cell_Receptor,Fc epsilon RI,
Protein Expression Peripheral blood,
Subcellular Localization extracellular region,extracellular space,intracellular,
Protein Function function:Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.,online information:Clinical information on Leukine,pharmaceutical:Available under the names Leukine (Immunex) and Leucomax (Novartis). Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.,polymorphism:Variant Ile-117 may be a risk factor for atopic asthma.,similarity:Belongs to the GM-CSF family.,subunit:Monomer.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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