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ITT6036

ITT6036
ITT6036-2
ITT6036
ITT6036-2
ITT6036
  • Catalog: ITT6036
  • Gene/Protein: CD300A CMRF35H IGSF12 HSPC083
  • Product Description: Immunotag™ CD300a Polyclonal Antibody
334.0000
Price in reward points: 334

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Immunotag™ CD300a Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD300a
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution IHC-p 1:50-200, ELISA 1:10000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthetic peptide from human protein at AA range: 141-190
Specificity The antibody detects endogenous CD300a
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CD300A CMRF35H IGSF12 HSPC083
Accession No. Q9UGN4 Q6SJQ0
Alternate Names CMRF35-like molecule 8 (CLM-8) (CD300 antigen-like family member A) (CMRF-35-H9) (CMRF35-H9) (CMRF35-H) (IRC1/IRC2) (Immunoglobulin superfamily member 12) (IgSF12) (Inhibitory receptor protein 60) (IRp60) (NK inhibitory receptor) (CD antigen CD300a)
Description CD300a molecule(CD300A) Homo sapiens This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],
Protein Expression Blood,Cord blood,Lymphoid,
Subcellular Localization plasma membrane,membrane,integral component of membrane,extracellular exosome,
Protein Function function:Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.,tissue specificity:Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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