ITT6049
ITT6049
- Catalog: ITT6049
- Gene/Protein: GZMM MET1
- Product Description: Immunotag™ Granzyme M Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Granzyme M |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 207-256 |
| Specificity | The antibody detects endogenous Granzyme M |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GZMM MET1 |
| Accession No. | P51124 |
| Alternate Names | Granzyme M (EC 3.4.21.-) (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease) |
| Description | granzyme M(GZMM) Homo sapiens Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012], |
| Protein Expression | Pancreas,Spleen, |
| Subcellular Localization | extracellular region,membrane, |
| Protein Function | function:Cleaves peptide substrates after methionine, leucine, and norleucine.,similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,subcellular location:Granules of large granular lymphocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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