ITT6079
ITT6079
- Catalog: ITT6079
- Gene/Protein: ATP6AP1
- Product Description: Immunotag™ V-ATPase S1 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | V-ATPase S1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human V-ATPase S1. at AA range: 421-470 |
Specificity | V-ATPase S1 Polyclonal Antibody detects endogenous levels of V-ATPase S1 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ATP6AP1 |
Accession No. | Q15904 Q9R1Q9 |
Alternate Names | V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1) |
Description | ATPase H+ transporting accessory protein 1(ATP6AP1) Homo sapiens This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013], |
Cell Pathway/ Category | Oxidative phosphorylation,Lysosome,Vibrio cholerae infection,Epithelial cell signaling in Helicobacter pylori infection, |
Protein Expression | Brain,Kidney,Liver,Spleen,Testis, |
Subcellular Localization | vacuolar membrane,endosome membrane,integral component of membrane,proton-transporting two-sector ATPase complex,proton-transporting V-type ATPase, V1 domain,extracellular exosome, |
Protein Function | function:Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.,similarity:Belongs to the vacuolar ATPase subunit S1 family.,subunit:Composed of at least 10 subunits.,tissue specificity:Ubiquitous., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |