Immobilized Pepstatin (3 Citations)
Catalog
Description
Size
Price(USD)
Qty
Catalog
786-789
786-789
Description
Immobilized Pepstatin
Immobilized Pepstatin
Size
5ml resin
5ml resin
$384.00
$384.00
G-Biosciences Immobilized Pepstatin is for the purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin.
Pepstatin is isovaleryl-Val-Val-AHMHA-Ala-AHMHA where AHMHA= (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid and is a potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases.
The resin consists of 6% beaded agarose that is covalently coupled to pepstatin through a diaminodipropylamine spacer arm and has a binding capacity of 1-2mg pepsin per millimeter of settled resin.
Features
- Capacity: 1-2mg pepsin/ml resin
- 6% beaded agarose
- Diaminodipropylamine spacer arm
Applications
- Purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin
- Azadi, Mohammad Ali et al (2021) A psychrophilic caseinolytic aspartic protease from the freshwater amphipod Gammarus bakhteyaricus for application in ilk coagulation. LWT. https://doi.org/10.1016/j.lwt.2021.112536
- Mohammadi, Soheila et al (2021) Extraction, purification and characterization of a thermally stable aspartic protease from freshwater shrimp Gammarus sp. with a high catalytic efficiency. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY. https://doi.org/10.1016/j.bcab.2021.102224
- Bee, J.S. et al (2015) Biotechnol Prog DOI: 10.1002/btpr.2150