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Protease & Protease Inhibitor Systems

Download the Protease & Phosphatase Inhibitors, Enzymes & Assays Hanbook

 

Our Protease & Protease Inhibitor Systems include proteases, protease assays and screening systems, and protease inhibitors. A large variety of mass spectrometry, sequencing grade and general proteases are offered including Proteinase K, a high activity, non-specific serine protease, our partially purified Trypsin for general use and mass spectrometry grade MSG-Trypsin.

 

A selection of assays and screening systems for the detection of proteases are also available. We have protease activity assays such as our Protease Screening Kit and Protease Assay Kit. To identify destructive proteases, we offer ProteSEEKER. We also offer Fluoro™ Protease Assay, a fluorometric, quantitative protease assay. Both resorufin and FITC Casein protease substrates are also available.

 

A range of protease inhibitor cocktails and individual inhibitors can be found in our protease inhibitor section. ProteaseArrest has been proven to inhibit >95% of protease enzyme activity making it 80% more effective than tablet cocktail formats. Superior enzyme inhibition can also be achieved using our dry format inhibitor cocktail, ProteCEASE.

proteasearrest-an1-cta

[(S)-1-Carboxy-2-Phenyl]-carbamoyl-Arg-Val-arginal   Specificity:  Inhibits Ca2+-dependent endopeptidases, including papain, trypsin-like serine proteases, some cysteine proteases and to a lesser extent plasmin.  Higher specificity for trypsin and papain compared to leupeptin. &nb..
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Also known as bovine pancreatic trypsin inhibitor.     Activity: Approx 6,000 KIU/mg   Specificity:  A broad range, competitive and reversible inhibitor of chymotrypsin, plasmin, trypsin, kallikrein and other serine proteases     Solubility: Soluble in water (Stoc..
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N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride     Specificity: Competitive inhibitor of surface aminopeptidases, including aminopeptidase B (Ki=2nM), leucine aminopeptidase (Ki=20nM). Also inhibits aminopeptidases N; does not inhibit endoproteases.     ..
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N-[(S)-1-carboxy-isopentyl)-carbamoyl-alpha-(2-iminohexahydro-4(S)-pyrimidyl]-L-glycyl-L-phenylalaninal     Specificity: Inhibits serine proteases having a chymotrypsin-like specificity, including α, β γ, and δ chymotrypsin, and most cysteine proteases including ca..
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E-64 L-trans-epoxysuccinyl-leucylamide-(4-guanido)-butane or N-[N-(L-trans-carboxyoxiran-2-carbonyl)-L-leucyl]-agmatine   Features CAS Number: 66701-25-5 Molecular Formula : C₁₅H₂₇Nâ‚…Oâ..
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EDTA disodium salt is a reversible metalloprotease inhibitor that is used for chelating metal ions. A 0.5M solution is also available.   Chemical Name: EDTA (Ethylenediaminetetracetic acid)   Synonyms: disodium ethylenediaminetetraacetate dihydrate; ethylenediamine tetraacetic acid d..
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Features Specificity: Inhibits serine, plasmin, porcine kallikrein and cysteine proteases, including papain and cathepsin B. Does not inhibit chymotrypsin and thrombin. Molecular weight: 475.59 Purity: Three tautomeric isomers in solution Solubility: Soluble in H2O (50mg/ml..
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Isovaleryl-Val-Val-AHMHA-Ala-AHMHA where AHMHA= (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid   Specificity: A potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases.   Solubility: Soluble in DMSO or met..
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N-alpha-L-rhamnopyranosyloxy(hydroxyphosphinyl)-L-Leucyl-L-Tryptophan   Specificity: Inhibits some metalloproteases, including thermolysin, collagenase and bacterial metallo proteases from Bacillus subtilis, Streptomyces griseus and Pseudomonas aeruginosa (metallo elastase).   Solubili..
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Features Synonyms: α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride CAS Number: 329-98-6 Molecular Formula: C₇H₇FOâ‚‚S Molecular Weight: 174.19 g/mol Activity: >99.9% Solubility: Soluble in..
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