Sulfo SHPP (Water Soluble Bolton Hunter Reagent)

G-Biosciences water-soluble Bolton-Hunter Reagent (Sulfo-SHPP) conjugates tyrosine-like groups to end-terminal α-amino groups or ε-amino groups of lysine to increase the number of tyrosyl groups that can be iodinated by iodine-125 labeling procedures.

Radioactive iodine (¹²⁵I) is routinely used by researchers to label proteins. The iodination of proteins can be performed enzymatically or chemically. The Bolton-Hunter reagent is designed to aid the labeling of proteins with radioactive iodine.

Protein modification kit related to Sulfo-SHPP with buffer is also avaialble [Tyrosine Addition Kit]

Click here for the original Bolton-Hunter reagent.

Features

• Synonyms: Sulfosuccinimidyl-3-(4-hydroxyphenyl) propionate; Sulfo SHPP; Water Soluble Bolton-Hunter Reagent
• CAS Number: 106827-57-0
• Molecular Weight: 365.3
• Ideal for proteins with masked or no tyrosine residues
• Optimal reaction at pH 8.5
• Water soluble