The bis-glucose compounds have a tetradhedral chiral carbon with two polar headgroups (the glucose moieties) and a long hydrophobic fluorinated tail. In this way they resemble the neo-pentyl glycol detergents, such as LMNG that have seen some recent success in structural biology.
Specifications
- Compound Name: DDG
- IUPAC Name: N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(decylthio)propanamide
- Application: Membrane Protein Extraction
- Surfactant type: Hydrogenated surfactant with a bis-glucose head group
- Molecular Formula: C29H55NO13S
- Molecular Weight: 657.8 g/mol
- Percent Composition: C (52.95%), H (8.43%), N (2.13%), O (31.62%), S (4.87%)
- Purity (HPLC, 214nm): ≤95%
- Retention time (RP18 HPLC): tR = 14.6 min
- Physical State: White powder
- Stability: Store in <-20°C freezer for up to one year
- Solubility: Soluble in water (27 mM), methanol and DMSO
- Critical Micelle Concentration: 0.54 mM