Tetracycline is a bacteriostatic antibiotic with activity against both gram-positive and gram-negative bacteria. Within the cell tetracycline binds reversibly to the 30S subunit of the ribosome, preventing the binding of aminoacyl tRNA and inhibiting protein synthesis and hence cell growth.
Immobilized Tetracycline is made by covalentlly coupling tetracycline to 6% cross linked agarose and is used for isolating tetracycline binding proteins, receptors and antibodies
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Tetracycline coupled to 6% cross-linked Agarose
Coupling is covalent through linkage of amino or carboxyl group depending upon the antibiotic to the pre-activated agarose.
Available in 5 ml and 10 ml sizes
Immobilized Tetracycline is used for purification of tetracycline binding proteins or receptors or specific antibodies.