Staurosporine

Staurosporine is a strong inhibitor of phosphalipid/Ca2+ dependent protein kinase and platelet aggregation. It is most commonly used as an inducer of apoptosis in several mammalian cell types. It is also used to study role of protein kinases in signal transduction as it inhibits other protein kinases such as cAMP- and cGMP-dependent protein kinase.

Specifications:

• Source: Streptomyces sp.
• Molecular Formula: C28H26N4O3
• Molecular weight: 466.53
• Purity: free base, >99% 
• Cas Number: 62996-74-1
• Form: Lyophilized powder

Application(s)

• Staurosporine is used most commonly as inducer of apoptosis.
• It inhibits several protein kinases such as phosphalipid/Ca2+ dependent protein kinase, cAMP- and cGMP-dependent protein kinase and thus used in signal transduction studies