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Minoxidil

Minoxidil
Minoxidil
Minoxidil
Catalog Description Size Price (USD) Qty
GBM-1214-100MGMinoxidil100mg$105.00
GBM-1214-500MGMinoxidil500mg$420.00
K-ATP channel opener
Bioassays Specification
Bio-Activity K-ATP channel opener
Chemical Name 6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide
Function / Pharmacology Minoxidil is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle.1 Active metabolite is Minoxidil sulfate (IC50 = 0.14 µM). Mainly used as a treatment for alopecia because of its observed hair regrowth ability.2
CAS# 38304-91-5
MW 209.25
Molecular Formula C9H15N5O
Solubility Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).
Supplied powder
Storage as supplied RT
Ship temp Ambient
References 1) Meisheri et al. (1988), Mechanism of action of minoxidil sulfate-induced vsodialtion: a role for increased K+ permeability. J.Pharmacol.Exp.Ther., 245 7 / 2) Messenger and Rundegren (2004) Minoxidil:mechanisms of action on hair growth. Br.J.Dermatol. 150 186
Protein Specification
Purity >98%

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