Minoxidil
Minoxidil
Minoxidil
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-1214-100MG | Minoxidil | 100mg | $105.00 | |
| GBM-1214-500MG | Minoxidil | 500mg | $420.00 |
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Description
K-ATP channel opener
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Specifications
Bioassays Specification Bio-Activity K-ATP channel opener Chemical Name 6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide Function / Pharmacology Minoxidil is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle.1 Active metabolite is Minoxidil sulfate (IC50 = 0.14 µM). Mainly used as a treatment for alopecia because of its observed hair regrowth ability.2 CAS# 38304-91-5 MW 209.25 Molecular Formula C9H15N5O Solubility Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml). Supplied powder Storage as supplied RT Ship temp Ambient References 1) Meisheri et al. (1988), Mechanism of action of minoxidil sulfate-induced vsodialtion: a role for increased K+ permeability. J.Pharmacol.Exp.Ther., 245 7 / 2) Messenger and Rundegren (2004) Minoxidil:mechanisms of action on hair growth. Br.J.Dermatol. 150 186 Protein Specification Purity >98% - Reviews
| Bioassays Specification | |
| Bio-Activity | K-ATP channel opener |
| Chemical Name | 6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide |
| Function / Pharmacology | Minoxidil is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle.1 Active metabolite is Minoxidil sulfate (IC50 = 0.14 µM). Mainly used as a treatment for alopecia because of its observed hair regrowth ability.2 |
| CAS# | 38304-91-5 |
| MW | 209.25 |
| Molecular Formula | C9H15N5O |
| Solubility | Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml). |
| Supplied | powder |
| Storage as supplied | RT |
| Ship temp | Ambient |
| References | 1) Meisheri et al. (1988), Mechanism of action of minoxidil sulfate-induced vsodialtion: a role for increased K+ permeability. J.Pharmacol.Exp.Ther., 245 7 / 2) Messenger and Rundegren (2004) Minoxidil:mechanisms of action on hair growth. Br.J.Dermatol. 150 186 |
| Protein Specification | |
| Purity | >98% |