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Zwitterionic Detergents

Zwitterionic detergents protect the native state of proteins without altering the native charge of the protein molecules. Zwitterionic detergents are used for isoelectric focusing  and 2D electrophoresis. Synthetic zwitterionic detergents are known as sulfobetaines. Sulfobetaines retain their zwitterionic characteristics over a wide range of pH. The following zwitterionic detergents are the most efficient and widely used for 2D gel electrophoresis.

 

Download the Detergents Handbook & Selection Guide for Complete Listings

Type: Zwitterionic detergent   Full Name: Amidosulfobetaine-14   Molecular Formula: C22H46N2O4S   Molecular Weight: 434.7   Form: White to off white powder   Purity: >99%   Solubility: Water soluble   Conductivity: <50µS in a 10% solu..
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Type: Zwitterionic detergent   Full Name: 4-n-Octylbenzoylamido-propyl-dimethylammonio sulfobetaine   Molecular Formula: C23H40N2O4S   Molecular Weight: 440.6   Form: Off white powder   Purity: >99%    Solubility: Water soluble   Applications..
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Type: Zwitterionic detergent   Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate   Mol. Formula: C32H58N2O7S   Mol Weight: 614.9   Form: White solid   Purity: >99%   Solubility: Water soluble   Conductivity: <25µS..
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Type: Zwitterionic detergent   Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate   Molecular Formula: C32H58N2O8S   Molecular Weight: 630.9   Form: White solid   Purity: >99%   Solubility: Water soluble   Conductivity: ..
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Type: Non-detergent sulfobetaine   Full Name: 3-(1-Pyridino)-1-propane sulfonate   Molecular Formula: C8H11NO3S   Molecular Weight: 201.4   Form: White Powder   Purity: >99%   Solubility: Water   Applications ND SB 201 is a Zwitterionic ..
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Type: Zwitterionic detergent   Full Name: N-Decyl-N,N-dimethyl-3-ammonio-1-propanesulfonate   Molecular Formula: CH3(CH2)9N+(CH3)2CH2CH2CH2SO3   Molecular Weight: 307.5   Form: White solid   Purity: >99%   Solubility: Water soluble   Critical micel..
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Type: Zwitterionic detergent   Full Name: N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate   Molecular  Formula: CH3(CH2)11N+(CH3)2CH2CH2CH2SO3-   Molecular Weight: 335.5   Form: White solid   Purity: >99%   Solubility: Water soluble   Crit..
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Type: Zwitterionic detergent   Full Name: N-Tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate   Molecular Formula: CH3(CH2)13N+(CH3)2CH2CH2CH2SO3-   Molecular Weight: 364.0   Form: White solid   Purity: >99%   Solubility: Water soluble   Critica..
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ASB-16 is a zwitterionic detergents composed of a sulfobetaine with a C16 alkyl tail that is highly efficient in solubilizing proteins for 2D electrophoresis analysis and other downstream applications.  Optimal solubility is achieved in Urea and thiourea buffers, but not in urea alone.  ..
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