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Bioassays

Download the Bioassay Handbook & Selection Guide for Complete Product Listing

 

Our Bioassays cover a wide range of proteomic and cell biology fields. Our CytoScan products offer a range of
non-radioactive bioassays for the study of chemical and cell-mediated cytotoxicity, viability, cell death or cell proliferation. Included are cell proliferation and cell toxicity assays which feature lactate dehydrogenase (LDH) assays, WST-1 assays and  sulforhodamine B (SRB) assays. Our apoptotic line features caspase assays and a wide selection of inhibitors.

 
An array of highly sensitive protein quantification assays are available including NI(Non-Interfering) protein assay, a colorimetric protein assay that overcomes interference of common laboratory agents, and our CB-X  assay which is designed to be compatible with all commonly used buffers and conditions.

 

We offer continuous enzyme coupled assays for methylation that can continuously monitor SAM-dependent methyltransferases without the use of radioactive labels or endpoint measurements.

 

We have a phosphatase assay for the quantification of phosphatases and three phosphatase inhibitor cocktails to inhibit phosphatases and for phosphatase studies.

 
PEROXsay Peroxide Assays and a variety of enzymes are also available.
A class of polypeptide antibiotics isolated from the Steptomyces soil bacteria.  Actinomycin D inhibits transcription by binding to DNA at the transcription initiation complex and therefore preventing elongation by the RNA polymerase.   Supplied as 50μl 10mM solution.   Featur..
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Adenine Deaminase (EC 3.5.4.2) converts Adenine to Hypoxanthine.   A highly purified recombinant enzyme protein supplied at a 2µM concentration...
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Adenosylhomocysteine nucleosidase (EC 3.2.2.9) converts S-adenosylhomocysteine (AdoHcy) to S-(deoxy-D-ribos-5-yl)-L-homocysteine + adenine.   A highly purified recombinant enzyme protein supplied at a 10µM concentration...
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AlamarBlue Cell Viability Assay reagent quantitatively measures the proliferation of mammalian cell lines, bacteria and fungi. The dye incorporates an oxidation-reduction (REDOX) indicator that both fluoresces and change color in response to the chemical reduction of growth medium due to cell growth..
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Anthocyanins represent the most important group of water-soluble pigments in the visible region detectable by the human eye. These pigments are responsible for the different colors ranging from red to blue present in various fruits, vegetables and cereals, accumulated in cell vacuoles. Anthocyanins ..
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The Apoptotic DNA Ladder kit contains all of the reagents necessary for the preparation of cellular fractions for the production of apoptosis nucleosomal DNA ladders. The kit does not require the use of toxic phenol. The protocol involves: cell lysis; removal of cellular debris; and precipitation of..
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Ready-to-use high quality apoptosis inducers allow users an easy tool for induction of apoptosis in cultured cells. These stabilized reagent solutions have a long storage life and are easy to use. The selection of apoptosis inducers include actinomycin D, camptothecin, cycloheximide, dexamethasone, ..
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4-ethyl-4-hydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b] quinoline-3,14-(4H,12H)-dione     A cytotoxic quinoline alkaloid that inhibits the DNA enzyme topoisomerase I (Topo I). Supplied as 1ml 2mM   Features Synonym: CPT CAS Number: 7689-03-4 Linear Formula: C20H1..
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The CasPASE™ Apoptosis Colorimetric Assay provides a simple and easy to follow method for assaying caspases, a key early indicator of apoptosis in mammalian cells. The assay is based on the detection of cleavage of a synthetic substrate, which is labeled with the chromophore ρ-nitroanilin..
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The Caspase inhibitors are potent fluoromethyl ketone (FMK) based, non-toxic, and membrane permeable. Inhibitors are supplied as 1mM ready-to-use solutions and are recommended for use at 1µl/ml cell culture or in caspase assays.  ..
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The CasPASE™ Apoptosis assays are designed to monitor apoptosis by measuring various caspase (protease) activities, a key early indicator of apoptosis in mammalian cells. The assay provides a simple and easy to follow method that can be monitored with a fluorescence reader. The assay is based..
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Catalase is an enzyme present in blood and other tissues with antioxidant activity. This enzyme can catalyze the reaction that consumes hydrogen peroxide, transforming it into water and oxygen. Since hydrogen peroxide is difficult to be measured directly in biological samples, the determination of t..
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