Mitochondrial Assays

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Mitochondria are referred to as “power-houses of cell” as they generate the majority of cellular ATP via oxidative phosphorylation. Furthermore, ß-oxidation of short-, medium and long- chain fatty acids is carried in mitochondria and mitochondria are involved in ROS generation and apoptosis. Mitochondria also play a key role in intermediary metabolism. 
Mitochondrial dysfunction has been linked to variety of market therapeutics and also to several pathological diseases. Therefore studying or checking mitochondrial health is paramount to cell health. 
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FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone]

FCCP [Carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone] is a potent uncoupler of oxidative phosphorylation in mitochondria. It is used as a positive control for mitochondrial membrane depolarizat..

JC-1 Mitochondrial Membrane Potential Assay

JC-1 Mitochondrial Membrane Potential Assay comprise of lipophilic cationic fluorescent dye; 5,5,6,6’-tetrachloro-1,1’,3,3’-tetraethylbenzimi-dazoylcarbocyanine iodide (JC-1). In hea..

TMRE Mitochondrial Membrane Potential Assay

TMRE Mitochondrial Membrane Potential Assay quantifies changes in mitochondrial membrane potential of live cells via microplate fluorometry, fluorescence microscopy and flow cytometry. Tetramethylr..