Protease & Protease Inhibitor Systems

Download the Protease & Phosphatase Inhibitors, Enzymes & Assays Hanbook


Our Protease & Protease Inhibitor Systems include proteases, protease assays and screening systems, and protease inhibitors. A large variety of mass spectrometry, sequencing grade and general proteases are offered including Proteinase K, a high activity, non-specific serine protease, our partially purified Trypsin for general use and mass spectrometry grade MSG-Trypsin.


A selection of assays and screening systems for the detection of proteases are also available. We have protease activity assays such as our Protease Screening Kit and Protease Assay Kit. To identify destructive proteases, we offer ProteSEEKER. We also offer Fluoro™ Protease Assay, a fluorometric, quantitative protease assay. Both resorufin and FITC Casein protease substrates are also available.


A range of protease inhibitor cocktails and individual inhibitors can be found in our protease inhibitor section. ProteaseArrest has been proven to inhibit >95% of protease enzyme activity making it 80% more effective than tablet cocktail formats. Superior enzyme inhibition can also be achieved using our dry format inhibitor cocktail, ProteCEASE.


Sort By:


4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride   Specificity: Specific irreversible inhibitor of serine proteases, including chymotrypsin, kallikrein, plasmin, thrombin and trypsin..


Calpain inhibitor I; N-[N-(N-Acetyl-L-leucyl)-L-leucyl]-L-norleucine   Specificity: Cell permeable peptide aldehyde inhibitor of calpain I and to a lesser extent calpain II.  Also inhi..

Antipain Dihydrochloride

[(S)-1-Carboxy-2-Phenyl]-carbamoyl-Arg-Val-arginal   Specificity:  Inhibits Ca2+-dependent endopeptidases, including papain, trypsin-like serine proteases, some cysteine proteases an..


Also known as bovine pancreatic trypsin inhibitor.     Activity: Approx 6,000 KIU/mg   Specificity:  A broad range, competitive and reversible inhibitor of chymotrypsi..

Bacterial ProteaseArrest™

A broad range, 100X concentrated, ready-to-use protease inhibitor cocktail. Bacterial ProteaseArrest™ inhibits bacterial serine, cysteine and other bacterial specific proteases including aminope..

Bestatin HCl

N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride     Specificity: Competitive inhibitor of surface aminopeptidases, including aminopeptidase B (Ki=2nM), leucine a..


N-[(S)-1-carboxy-isopentyl)-carbamoyl-alpha-(2-iminohexahydro-4(S)-pyrimidyl]-L-glycyl-L-phenylalaninal     Specificity: Inhibits serine proteases having a chymotrypsin-like specifici..


E-64 L-trans-epoxysuccinyl-leucylamide-(4-guanido)-butane or N-[N-(L-trans-carboxyoxiran-2-carbonyl)-L-leucyl]-agmatine   Features CAS Number: 66701-25-5 Molecular Formula : C&a..

EDTA, disodium salt

EDTA disodium salt is a reversible metalloprotease inhibitor that is used for chelating metal ions. A 0.5M solution is also available.   Chemical Name: EDTA (Ethylenediaminetetracetic a..

Fluoro™ Protease Assay

The Fluoro™ Protease Assay Kit is designed for the quantitative determination of proteases present in a protein sample. The assay uses fluorescein isothiocyanate (FITC)-labeled casein as a gener..

FOCUS™ ProteaseArrest™

FOCUS™ ProteaseArrest™ is a ready-to-use, 100X concentrated, broad range protease inhibitor cocktail that is fully compatible with 2D electrophoresis and subsequent mass spectrometry. &..

Immobilized Ficin

Ficin (or Ficain) is a cysteine protease enzyme (EC isolated from fig latex is that has the endopeptidase activity to cleave immunoglobulin G molecules in the hinge reason. Ficin is typ..