| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-3414-5MG | P7C3-A20 | 5mg | $147.00 | |
| GBM-3414-25MG | P7C3-A20 | 25mg | $588.00 |
| Bioassays Specification | |
| Bio-Activity | NAMPT activator; Proneurogenic agent |
| Chemical Name | 3,6-dibromo-β-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine |
| Function / Pharmacology | A neuroprotective and proneurogenic agent acting via NAMPT stimulation1. Displays neuroprotection and promotes endogenous reparative functions after traumatic brain injury (TBI)2. Furthermore it repairs the blood-brain barrier, arrests chronic neurodegeneration and restores cognition one year after TBI in a mouse model3. P7C3-A20 exerts neuroprotective effects in a hypoxic-ischemic encephalopathy model4. Suppresses neuroinflammation and protects retinal ganglion cells from optic nerve crush in a rat model5. |
| CAS# | 1235481-90-9 |
| MW | 506.2 |
| Molecular Formula | C22H19Br2FN2O |
| Solubility | Soluble in DMSO (up to 40 mg/ml) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1. PM LoCoco et al. Elife 2017 6:e29626 2. MO Blaya et al. J. Neurotrauma. 2014 31:476 3. E Vazquez-Rosa et al. Proc. Natl. Acad. Sci. USA 2020 117:27667 4. J Bai et al. Neuroscience 2020 441:197 5. H Oku et al. Invest. Ophthalmol. Vis. Sci. 2017 58:4877 |
| Protein Specification | |
| Purity | >98% |
| Bioassays Specification | |
| Bio-Activity | NAMPT activator; Proneurogenic agent |
| Chemical Name | 3,6-dibromo-β-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine |
| Function / Pharmacology | A neuroprotective and proneurogenic agent acting via NAMPT stimulation1. Displays neuroprotection and promotes endogenous reparative functions after traumatic brain injury (TBI)2. Furthermore it repairs the blood-brain barrier, arrests chronic neurodegeneration and restores cognition one year after TBI in a mouse model3. P7C3-A20 exerts neuroprotective effects in a hypoxic-ischemic encephalopathy model4. Suppresses neuroinflammation and protects retinal ganglion cells from optic nerve crush in a rat model5. |
| CAS# | 1235481-90-9 |
| MW | 506.2 |
| Molecular Formula | C22H19Br2FN2O |
| Solubility | Soluble in DMSO (up to 40 mg/ml) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1. PM LoCoco et al. Elife 2017 6:e29626 2. MO Blaya et al. J. Neurotrauma. 2014 31:476 3. E Vazquez-Rosa et al. Proc. Natl. Acad. Sci. USA 2020 117:27667 4. J Bai et al. Neuroscience 2020 441:197 5. H Oku et al. Invest. Ophthalmol. Vis. Sci. 2017 58:4877 |
| Protein Specification | |
| Purity | >98% |
