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CHAPS (10 Citations)

Type: Zwitterionic detergent
 
Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
 
Mol. Formula: C32H58N2O7S
 
Mol Weight: 614.9
 


Form: White solid
 


Purity: >99%
 

Solubility: Water soluble
 


Conductivity: <25µS in a 10% solution
 


Critical micelle concentration (CMC): 6-10mM (25°C)
 


Aggregation number: 10
 


Cloud point: >100°C
 

Average micellar weight: 6150
 

Features

  • Zwitterionic detergent
  • Non-denaturing
  • Electrically neutral

 


Applications

  • Has all the advantages of sulfobetaine containing detergents: hydrophobic, bile salt, and anionic detergents in a single molecule.
  • Better at solubilizing proteins and breaking protein-protein interactions.
  • Less protein aggregation than non-ionic detergents.
  • Capable of solubilizing opiate receptors.
  • CHAPS can be removed from protein solutions with a detergent removing gel or by dialysis.

 

 

Material Safety Data Sheet
DG049
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DG050
English_US
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Finnish
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DG051
English_US
Danish
Dutch
English_UK
French
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Finnish
Swedish
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DG096
English_US
Danish
Dutch
English_UK
French
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Spanish
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Finnish
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DG097
English_US
Danish
Dutch
English_UK
French
German
Spanish
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Finnish
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DG098
English_US
Danish
Dutch
English_UK
French
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DG099
English_US
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Technical Literature
Assay Development A handbook for selection of products for assay development, including coated plates, blocking agents, antibodies, enzymes and antibody labeling tools.
Detergent Handbook & Selection Guide A Comprehensive Guide to the Properties and Uses of Detergents in Research. Also features information on detergent removal systems.
Removing Detergents from Protein Solutions
Certificate Of Analysis
DG049
102707
110308
110604
130605
212210
DG050
101407
212210
110308
111407
111901
112303
120409
121503
121607
130605
132002
132105
141305
092008
100102
100302
100505
100908
203011
DG051
180905
183011
190410
192905
203011
090812
100111
100505
100902
100908
101407
102602
102909
103003
110303
110308
110612
112206
212210
120409
121607
122205
122410
130509
130804
131712
132002
141305
150212
150308
151002
151106
151412
161810
DG096
101509
110308
110711
130605
132002
151002
180905
203011
212210
DG097
202901
101011
120406
132903
141504
DG098
202901
DG099
141504 rev3
160410
160410 rev2
161804
161804 ext
162106

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