| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| 786-2274 | Endonuclease VIII | 2,000 U | $125.00 |
Endonuclease VIII from E. coli has dual functions as an N-glycosylase and an AP-lyase. It removes damaged pyrimidines from double-stranded DNA to create an AP site. The AP-lyase activity then cleaves at this site, resulting in a 5′ phosphate and a 3′ phosphate. This enzyme targets damaged bases like thymine glycol and uracil glycol. Unlike Endonuclease III, which only has β lyase activity, Endonuclease VIII also exhibits δ lyase activity, enabling it to address a broader range of DNA damage.
Concentration: 10 U/µl
Storage: -20ºC
Endonuclease VIII from E. coli has dual functions as an N-glycosylase and an AP-lyase. It removes damaged pyrimidines from double-stranded DNA to create an AP site. The AP-lyase activity then cleaves at this site, resulting in a 5′ phosphate and a 3′ phosphate. This enzyme targets damaged bases like thymine glycol and uracil glycol. Unlike Endonuclease III, which only has β lyase activity, Endonuclease VIII also exhibits δ lyase activity, enabling it to address a broader range of DNA damage.
Concentration: 10 U/µl
Storage: -20ºC
