PP1
PP1
PP1
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-1184-5MG | PP1 | 5mg | $137.00 | |
| GBM-1184-25MG | PP1 | 25mg | $504.00 |
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-1184-5MG | PP1 | 5mg | $137.00 | |
| GBM-1184-25MG | PP1 | 25mg | $504.00 |
| Bioassays Specification | |
| Bio-Activity | Src family kinase inhibitor |
| Chemical Name | 4-amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine |
| Function / Pharmacology | Potent and selective inhibitor of Src family tyrosine kinases. IC50=5 nM (p65lck), IC50=6 nM(P59fynT), IC50=170 nM (p60src). Cell permeable. |
| CAS# | 172889-26-8 |
| MW | 281.63 |
| Molecular Formula | C16H19N5 |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml). |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Hanke et al. (1996), Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation; J. Biol. Chem., 271 695 |
| Protein Specification | |
| Purity | >98% |
| Bioassays Specification | |
| Bio-Activity | Src family kinase inhibitor |
| Chemical Name | 4-amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine |
| Function / Pharmacology | Potent and selective inhibitor of Src family tyrosine kinases. IC50=5 nM (p65lck), IC50=6 nM(P59fynT), IC50=170 nM (p60src). Cell permeable. |
| CAS# | 172889-26-8 |
| MW | 281.63 |
| Molecular Formula | C16H19N5 |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml). |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Hanke et al. (1996), Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation; J. Biol. Chem., 271 695 |
| Protein Specification | |
| Purity | >98% |