| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-1363-5MG | Mitoquinone | 5mg | $147.00 | |
| GBM-1363-25MG | Mitoquinone | 25mg | $504.00 |
| Bioassays Specification | |
| Bio-Activity | Mitochondria-targeted antioxidant |
| Chemical Name | 10-(6’-Ubiquinonyl)decyltriphenylphosphonium bromide |
| Function / Pharmacology | A mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects1. Displays beneficial effects in mouse models of Alzheimer’s disease2. Protects pancreatic β-cells against oxidative stress and improves insulin secretion3. Cell permeable. |
| CAS# | 444890-41-9 |
| MW | 663.6 |
| Molecular Formula | C37H44BrO4P |
| Solubility | Soluble in DMSO (up to 70 mg/ml) or in Ethanol (up to 30 mg/ml) |
| Supplied | wax |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Ghosh et al. (2010), Neuroprotection by a mitochondria-targeted drug in a Parkinson’s disease model; Free Radic. Biol. Med., 49 1674 2) McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703 3) Lim et al. (2011), Mitrochondria-targeted antioxidants protect pancreatic β-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity; Cell Physiol. Biochem., 28 873 |
| Protein Specification | |
| Purity | >98% |
| Bioassays Specification | |
| Bio-Activity | Mitochondria-targeted antioxidant |
| Chemical Name | 10-(6’-Ubiquinonyl)decyltriphenylphosphonium bromide |
| Function / Pharmacology | A mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects1. Displays beneficial effects in mouse models of Alzheimer’s disease2. Protects pancreatic β-cells against oxidative stress and improves insulin secretion3. Cell permeable. |
| CAS# | 444890-41-9 |
| MW | 663.6 |
| Molecular Formula | C37H44BrO4P |
| Solubility | Soluble in DMSO (up to 70 mg/ml) or in Ethanol (up to 30 mg/ml) |
| Supplied | wax |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Ghosh et al. (2010), Neuroprotection by a mitochondria-targeted drug in a Parkinson’s disease model; Free Radic. Biol. Med., 49 1674 2) McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703 3) Lim et al. (2011), Mitrochondria-targeted antioxidants protect pancreatic β-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity; Cell Physiol. Biochem., 28 873 |
| Protein Specification | |
| Purity | >98% |
