| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-2366-5MG | BML-210 | 5mg | $126.00 | |
| GBM-2366-25MG | BML-210 | 25mg | $504.00 |
| Bioassays Specification | |
| Bio-Activity | HDAC inhibitor |
| Chemical Name | N1-(2-Aminophenyl)-N8-phenyloctanediamide |
| Function / Pharmacology | A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines. |
| CAS# | 537034-17-6 |
| MW | 339.44 |
| Molecular Formula | C20H25N3O2 |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Savickiene, et al. (2006), The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines. Eur. J. Pharmacol. 549 9 / 2) Herman, et al. (2006), Histone deacetylase inhibitors reverse gene silencing in Friedreich’s ataxia. Nature Chem. Biol. 10 551 |
| Protein Specification | |
| Purity | >98% |
| Bioassays Specification | |
| Bio-Activity | HDAC inhibitor |
| Chemical Name | N1-(2-Aminophenyl)-N8-phenyloctanediamide |
| Function / Pharmacology | A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines. |
| CAS# | 537034-17-6 |
| MW | 339.44 |
| Molecular Formula | C20H25N3O2 |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Savickiene, et al. (2006), The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines. Eur. J. Pharmacol. 549 9 / 2) Herman, et al. (2006), Histone deacetylase inhibitors reverse gene silencing in Friedreich’s ataxia. Nature Chem. Biol. 10 551 |
| Protein Specification | |
| Purity | >98% |
