Mitoquinone mesylate
Mitoquinone mesylate
Mitoquinone mesylate
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-3914-5MG | Mitoquinone mesylate | 5mg | $147.00 | |
| GBM-3914-25MG | Mitoquinone mesylate | 25mg | $504.00 |
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Description
Mitochondria-targeted antioxidant
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Specifications
Bioassays Specification Bio-Activity Mitochondria-targeted antioxidant Chemical Name 10-(6’-Ubiquinonyl)decyltriphenylphosphonium mesylate Function / Pharmacology Mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects1. Displays beneficial effects in mouse models of Alzheimer’s disease2. Protects pancreatic β-cells against oxidative stress and improves insulin secretion3. Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels4. Inhibited mitochondrial fission and oxidative phosphorylation, and induced apoptosis in active hepatic stellate cells5. Cell permeable. CAS# 845959-50-4 MW 678.8 Molecular Formula C37H44O4P • CH3O3S Solubility Soluble in DMSO (up to 10 mg/ml) Supplied wax Storage as supplied -20°C Ship temp Ambient References 1. A Ghosh et al. Free Radic. Biol. Med. 2010 49:1674 2. MJ McManus et al. J. Neurosci. 2011 31:15703 3. S Lim et al. Cell Physiol. Biochem. 2011 28:873 4. MJ Hu et al. Cells 2019 8:1417 5. Y Zhou et al. Cell Death Dis. 2022 13:689 Antibody Specification Alternate Names MitoQ Protein Specification Purity >98% - Reviews
| Bioassays Specification | |
| Bio-Activity | Mitochondria-targeted antioxidant |
| Chemical Name | 10-(6’-Ubiquinonyl)decyltriphenylphosphonium mesylate |
| Function / Pharmacology | Mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects1. Displays beneficial effects in mouse models of Alzheimer’s disease2. Protects pancreatic β-cells against oxidative stress and improves insulin secretion3. Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels4. Inhibited mitochondrial fission and oxidative phosphorylation, and induced apoptosis in active hepatic stellate cells5. Cell permeable. |
| CAS# | 845959-50-4 |
| MW | 678.8 |
| Molecular Formula | C37H44O4P • CH3O3S |
| Solubility | Soluble in DMSO (up to 10 mg/ml) |
| Supplied | wax |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1. A Ghosh et al. Free Radic. Biol. Med. 2010 49:1674 2. MJ McManus et al. J. Neurosci. 2011 31:15703 3. S Lim et al. Cell Physiol. Biochem. 2011 28:873 4. MJ Hu et al. Cells 2019 8:1417 5. Y Zhou et al. Cell Death Dis. 2022 13:689 |
| Antibody Specification | |
| Alternate Names | MitoQ |
| Protein Specification | |
| Purity | >98% |