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Picotamide

Picotamide
Picotamide
Picotamide
Catalog Description Size Price (USD) Qty
GBM-3925-10MGPicotamide10mg$158.00
GBM-3925-50MGPicotamide50mg$620.00
TXA2 receptors and synthase inhibitor
Bioassays Specification
Bio-Activity TXA2 receptors and synthase inhibitor
Chemical Name 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide
Function / Pharmacology Picotamide is an antiplatelet agent that inhibits both thromboxane A2 and thromboxane A2 synthase.1-3
CAS# 32828-81-2
MW 376.4
Molecular Formula C21H20N4O3
Solubility Soluble in DMSO (up to at least 40 mg/ml) or in Ethanol (up to 5 mg/ml)
Supplied powder
Storage as supplied -20°C
Ship temp Ambient
References 1. Modesti, et al. (1989), Competitive inhibition of platelet thromboxane A2 receptor binding by picotamide; Eur. J. Pharmacol.. 169 85 2. Modesti, et al. (1991), Acute reduction of TxA2 platelet binding sites after in vivo administration of a TxA2 inhibitor; Br. J. Pharmacol.. 31 439 3 Ratti et al. (1998), Picotamide, an antithromboxane agent. Inhibits the migration and proliferation of arterial myocytes; J. Pharmacol. 355 77
Protein Specification
Purity >98%

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