Picotamide
Picotamide
Picotamide
| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-3925-10MG | Picotamide | 10mg | $158.00 | |
| GBM-3925-50MG | Picotamide | 50mg | $620.00 |
-
Description
TXA2 receptors and synthase inhibitor
-
Specifications
Bioassays Specification Bio-Activity TXA2 receptors and synthase inhibitor Chemical Name 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide Function / Pharmacology Picotamide is an antiplatelet agent that inhibits both thromboxane A2 and thromboxane A2 synthase.1-3 CAS# 32828-81-2 MW 376.4 Molecular Formula C21H20N4O3 Solubility Soluble in DMSO (up to at least 40 mg/ml) or in Ethanol (up to 5 mg/ml) Supplied powder Storage as supplied -20°C Ship temp Ambient References 1. Modesti, et al. (1989), Competitive inhibition of platelet thromboxane A2 receptor binding by picotamide; Eur. J. Pharmacol.. 169 85 2. Modesti, et al. (1991), Acute reduction of TxA2 platelet binding sites after in vivo administration of a TxA2 inhibitor; Br. J. Pharmacol.. 31 439 3 Ratti et al. (1998), Picotamide, an antithromboxane agent. Inhibits the migration and proliferation of arterial myocytes; J. Pharmacol. 355 77 Protein Specification Purity >98% - Reviews
| Bioassays Specification | |
| Bio-Activity | TXA2 receptors and synthase inhibitor |
| Chemical Name | 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide |
| Function / Pharmacology | Picotamide is an antiplatelet agent that inhibits both thromboxane A2 and thromboxane A2 synthase.1-3 |
| CAS# | 32828-81-2 |
| MW | 376.4 |
| Molecular Formula | C21H20N4O3 |
| Solubility | Soluble in DMSO (up to at least 40 mg/ml) or in Ethanol (up to 5 mg/ml) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1. Modesti, et al. (1989), Competitive inhibition of platelet thromboxane A2 receptor binding by picotamide; Eur. J. Pharmacol.. 169 85 2. Modesti, et al. (1991), Acute reduction of TxA2 platelet binding sites after in vivo administration of a TxA2 inhibitor; Br. J. Pharmacol.. 31 439 3 Ratti et al. (1998), Picotamide, an antithromboxane agent. Inhibits the migration and proliferation of arterial myocytes; J. Pharmacol. 355 77 |
| Protein Specification | |
| Purity | >98% |