ITA0089
ITA0089
- Catalog: ITA0089
- Gene/Protein: E2F4
- Product Description: Immunotag™ E2F4 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | E2F4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,IF/ICC,ELISA |
Recommended Dilution | WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human E2F4 |
Specificity | E2F4 antibody detects endogenous levels of total E2F4 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | E2F4 |
Accession No. | Q16254/Q15329 |
Alternate Names | E2F 4; E2F transcription factor 4; E2F transcription factor 4 p107/p130 binding; E2F-4; E2F4; E2F4_HUMAN; p107/p130 binding protein; Transcription factor E2F 4; Transcription factor E2F4; E2F 5; E2F transcription factor 5; E2F transcription factor 5 p130 binding; E2F-5; E2f5; E2F5_HUMAN; p130 binding; Transcription factor E2F5; |
Description | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 44kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |