ITA0281
ITA0281
ITA0281
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$526.00
Price in reward points: 526
- Catalog: ITA0281
- Gene/Protein: TADA2A
- Product Description: Immunotag™ ADA2L Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein ADA2L Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF/ICC,ELISA Recommended Dilution WB: 1:500~1:3000, IF/ICC 1:100-1:500 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide derived from human ADA2L Specificity ADA2L antibody detects endogenous levels of total ADA2L Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name TADA2A Accession No. O75478 Alternate Names ADA2 ALPHA; ADA2; ADA2 like; ADA2 like protein; ADA2, yeast, homolog of, alpha; ADA2A; hADA2; KL04P; Tada2l; Transcriptional adapter 2 alpha; Transcriptional adapter 2 like; Transcriptional adaptor 2 (ADA2 homolog, yeast) like; Transcriptional adaptor 2 (ADA2, yeast, homolog) like; Transcriptional adaptor 2 alpha; Transcriptional adaptor 2A; Description Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376). Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 47kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | ADA2L |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB: 1:500~1:3000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human ADA2L |
| Specificity | ADA2L antibody detects endogenous levels of total ADA2L |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | TADA2A |
| Accession No. | O75478 |
| Alternate Names | ADA2 ALPHA; ADA2; ADA2 like; ADA2 like protein; ADA2, yeast, homolog of, alpha; ADA2A; hADA2; KL04P; Tada2l; Transcriptional adapter 2 alpha; Transcriptional adapter 2 like; Transcriptional adaptor 2 (ADA2 homolog, yeast) like; Transcriptional adaptor 2 (ADA2, yeast, homolog) like; Transcriptional adaptor 2 alpha; Transcriptional adaptor 2A; |
| Description | Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 47kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |