ITA0631
ITA0631
- Catalog: ITA0631
- Gene/Protein: RYR2
- Product Description: Immunotag™ Phospho-RYR2( Ser2814) Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | Phospho-RYR2( Ser2814) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC |
| Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Dog |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human RYR2 around the phosphorylation site of Ser2814. |
| Specificity | Phospho-RYR2( Ser2814) Antibody detects endogenous levels of RYR2. |
| Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | RYR2 |
| Accession No. | Q92736 |
| Alternate Names | ARVC2; ARVD2; Cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; hRYR-2; ryanodine receptor 2 (cardiac); Ryanodine receptor 2; RyR; RYR-2; RyR2; RYR2_HUMAN; Type 2 ryanodine receptor; VTSIP; |
| Description | Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 564 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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