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ITA1518

ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
ITA1518
from
$526.00
Price in reward points: 526
  • Catalog: ITA1518
  • Gene/Protein: ITGB4
  • Product Description: Immunotag™ Integrin β4 Antibody

Available Options

Immunotag™ Integrin β4 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein Integrin β4
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,IF/ICC,ELISA
Recommended Dilution WB 1:500-1:2000,IHC 1:50-1:200, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human Integrin β4
Specificity Integrin β4 Antibody detects endogenous levels of total Integrin β4
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name ITGB4
Accession No. P16144
Alternate Names CD 104; CD104; CD104 antigen; gp150; Integrin beta 4 subunit; Integrin beta-4; ITB4_HUMAN; ITG B4; ITGB 4; Itgb4;
Description Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 202 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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