ITA1562
ITA1562
ITA1562
from
$526.00
Price in reward points: 526
- Catalog: ITA1562
- Gene/Protein: MEF2C
- Product Description: Immunotag™ MEF2C Antibody
-
Description
-
Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein MEF2C Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF/ICC,ELISA,CHIP,IHC-P,IHC-F Recommended Dilution IHC 1:50-1:200-P, ChIP, ICC/IF 1:100-1:500, WB 1:500-1:2000,, IHC-f 1:50-1:200 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen A synthesized peptide derived from human MEF2C Specificity MEF2C Antibody detects endogenous levels of total MEF2C Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name MEF2C Accession No. Q06413 Alternate Names C5DELq14.3; DEL5q14.3; MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C); MADS box transcription enhancer factor 2, polypeptide C; MEF2C; MEF2C_HUMAN; Myocyte enhancer factor 2C; Myocyte specific enhancer factor 2C; Myocyte-specific enhancer factor 2C; OTTHUMP00000222409; Similar to MADS box transcription enhancer factor 2 polypeptide C; Description Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 51 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | MEF2C |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA,CHIP,IHC-P,IHC-F |
| Recommended Dilution | IHC 1:50-1:200-P, ChIP, ICC/IF 1:100-1:500, WB 1:500-1:2000,, IHC-f 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human MEF2C |
| Specificity | MEF2C Antibody detects endogenous levels of total MEF2C |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | MEF2C |
| Accession No. | Q06413 |
| Alternate Names | C5DELq14.3; DEL5q14.3; MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C); MADS box transcription enhancer factor 2, polypeptide C; MEF2C; MEF2C_HUMAN; Myocyte enhancer factor 2C; Myocyte specific enhancer factor 2C; Myocyte-specific enhancer factor 2C; OTTHUMP00000222409; Similar to MADS box transcription enhancer factor 2 polypeptide C; |
| Description | Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 51 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |