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ITA1894

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ITA1894-3
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ITA1894
  • Catalog: ITA1894
  • Gene/Protein: CRK
  • Product Description: Immunotag™ CrkII Antibody
385.0000
Price in reward points: 385

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Immunotag™ CrkII Antibody
Antibody Specification
Datasheet

Target Protein CrkII
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,IF/ICC,ELISA
Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human CrkII
Specificity CrkII Antibody detects endogenous levels of total CrkII
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name CRK
Accession No. P46108
Alternate Names Adapter molecule crk; Avian sarcoma virus CT10 (v crk) oncogene homolog; CRK; CRK isoform 2; CRK isoform II; CRK_HUMAN; CRKII; FLJ38130; OTTHUMP00000115366; OTTHUMP00000198330; p38; Proto oncogene C crk; Proto-oncogene C-crk; v crk avian sarcoma virus CT10 oncogene homolog; v crk sarcoma virus CT10 oncogene homolog; v crk sarcoma virus CT10 oncogene homolog (avian);
Description Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 40kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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