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ITA2059

ITA2059-2
ITA2059-1
ITA2059-2
ITA2059-1
  • Gene/Protein: ARRDC1
  • Product Description: Immunotag™ Arrdc1 Antibody
  • 280.0000
    Price in reward points: 280

    Available Options

ITA2059

Immunotag™ Arrdc1 Antibody
Antibody Specification
Datasheet

Target Protein Arrdc1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:1000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human Arrdc1
Specificity Arrdc1 Antibody detects endogenous levels of total Arrdc1
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name ARRDC1
Accession No. Q8N5I2
Alternate Names ARRD1_HUMAN; ARRDC 1; ARRDC1; Arrestin domain containing 1; Arrestin domain containing protein 1; Arrestin domain-containing protein 1; MGC40555; OTTHUMP00000022707; OTTHUMP00000022709; RP11-48C7.5;
Description Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 48kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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