ITA2215
ITA2215
- Catalog: ITA2215
- Gene/Protein: RAB11B
- Product Description: Immunotag™ Rab 11B Antibody
385.0000
Price in reward points: 385
Your shopping cart is empty!
Antibody Specification | |
Datasheet | |
Target Protein | Rab 11B |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,IF/ICC,ELISA |
Recommended Dilution | WB 1:1000 IHC 1:200, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human Rab 11B |
Specificity | Rab 11B Antibody detects endogenous levels of total Rab 11B |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | RAB11B |
Accession No. | Q15907 |
Alternate Names | GTP-binding protein ypt3; H YPT3; RAB11B; RAB11B member RAS oncogene family; Ras-related protein Rab-11B; RB11B_HUMAN; YPT3; |
Description | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 28kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |