ITA2337
ITA2337
- Catalog: ITA2337
- Gene/Protein: TSHZ3
- Product Description: Immunotag™ TSH3 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | TSH3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:1000-3000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human TSH3 |
Specificity | TSH3 Antibody detects endogenous levels of total TSH3 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | TSHZ3 |
Accession No. | Q63HK5 |
Alternate Names | KIAA1474; Teashirt homolog 3; TSH3; TSH3_HUMAN; TSHZ3; Zinc finger protein 537; |
Description | Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) (PubMed:19343227). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity). Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 119 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |