ITA2466
ITA2466
- Catalog: ITA2466
- Gene/Protein: CLEC6A
- Product Description: Immunotag™ CLEC6A Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | CLEC6A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:1000-3000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human CLEC6A |
| Specificity | CLEC6A Antibody detects endogenous levels of total CLEC6A |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | CLEC6A |
| Accession No. | Q6EIG7 |
| Alternate Names | C type lectin domain family 6 member A; C type lectin superfamily member 10; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; CLC6A_HUMAN; CLEC4N; CLEC4N, mouse, homolog of; Clec6a; CLECSF10; DC associated C type lectin 2; DC-associated C-type lectin 2; Dectin-2; Dectin2; Dendritic cell associated lectin 2; Dendritic cell-associated C-type lectin 2; |
| Description | Binds high-mannose carbohydrates in a Ca2+-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 24 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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