ITA2469
ITA2469
- Catalog: ITA2469
- Gene/Protein: BPIFA1
- Product Description: Immunotag™ PLUNC Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | PLUNC |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human PLUNC |
| Specificity | PLUNC Antibody detects endogenous levels of total PLUNC |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | BPIFA1 |
| Accession No. | Q9NP55 |
| Alternate Names | BPIFA1; bA49G10.5; LPLUNC3; Lung-specific protein X; LUNX; NASG; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; PLUNC; Protein Plunc; Secretory protein in upper respiratory tracts; SPLUNC1; SPURT; Tracheal epithelium-enriched protein; Von Ebner protein Hl; |
| Description | Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 27 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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