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ITA2710

ITA2710
ITA2710
ITA2710
ITA2710
ITA2710
ITA2710
ITA2710
from
$526.00
Price in reward points: 526
  • Catalog: ITA2710
  • Gene/Protein: CEMIP
  • Product Description: Immunotag™ KIAA1199 Antibody

Available Options

Immunotag™ KIAA1199 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein KIAA1199
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC
Recommended Dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human KIAA1199.
Specificity KIAA1199 antibody detects endogenous levels of KIAA1199.
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name CEMIP
Accession No. Q8WUJ3
Alternate Names IR2155535; KIAA1199 protein; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; Transmembrane protein 2 like;
Description Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 153 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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